阅读说明：本技术 通过激活Notch信号传导治疗血管阻塞 (Treatment of vascular obstruction by activation of Notch signaling ) 是由 王蓉 于 2019-07-25 设计创作，主要内容包括：本发明提供了用于治疗血流或循环不足的各种病症的新疗法。本文公开的新发明基于以下发现：动脉血管中Notch信号传导的增加对血流或循环和组织再生以及在动脉闭塞、收缩或其他血流减少后降低组织损伤具有有益作用。动脉中Notch信号传导的增加促进有益作用,包括急性血管扩张和/或动脉生成以及副动脉生长,并改进缺血或其他循环条件降低后的恢复。本发明还提供了用于将Notch激活剂递送至血管的医疗装置。(The present invention provides novel therapies for treating various conditions of inadequate blood flow or circulation. The new invention disclosed herein is based on the following findings: an increase in Notch signaling in arterial blood vessels has beneficial effects on blood flow or circulation and tissue regeneration as well as reducing tissue damage following arterial occlusion, constriction or other reduction in blood flow. An increase in Notch signaling in arteries promotes beneficial effects, including acute vasodilation and/or arteriogenesis and arteriolar growth, and improves recovery following ischemia or a decrease in other circulatory conditions. The invention also provides medical devices for delivering Notch activators to blood vessels.)