阅读说明：本技术 Mir-92a或mir-145在治疗安格曼综合征中的用途 (Use of MIR-92A or MIR-145 for treating angeman syndrome ) 是由 马修·杜林 于 2019-06-14 设计创作，主要内容包括：负调节SNHG14基因活性的微小RNA的表达可用于治疗安格曼综合征。用于治疗安格曼综合征的此类微小RNA包括例如MIR-92a和/或MIR-145及其类似物和变体。可以使用表达载体诸如例如AAV载体转导细胞以将MIR-92a和/或MIR-145引入到靶组织以治疗安格曼综合征。(The expression of micrornas that negatively regulate the activity of SNHG14 gene may be used to treat angmann syndrome. Such microRNAs useful in the treatment of Angerman syndrome include, for example, MIR-92a and/or MIR-145 and analogs and variants thereof. Cells can be transduced with expression vectors such as, for example, AAV vectors to introduce MIR-92a and/or MIR-145 to target tissues to treat angmann syndrome.)