阅读说明：本技术 用于治疗rna病毒感染的苯基/吡啶基-n-苯基/吡啶基衍生物 (phenyl/pyridyl-N-phenyl/pyridyl derivatives for the treatment of RNA viral infections ) 是由 D·谢雷 J·塔泽 F·马于托-贝茨尔 R·纳日曼 J·桑托 C·阿波利特 于 2019-07-09 设计创作，主要内容包括：本发明涉及式(Ie)的化合物或其药学上可接受的盐中的任一种：其中Y～1代表芳基基团,X～2代表-O-基团、-NH-基团、-S-基团、-CO-NH-基团、-NH-CO-NH-基团、-NH-CO-基团、-CH(OH)-基团、-CH(COOH)NH-基团、-CH(COOCH-3)NH-基团、-C(OH)(CH-2OH)-、(AA)基团,即(AA)、包含1、2、3个或杂原子的二价5-元杂芳族环、-SO-2-基团或-SO-2-NH-基团,Y～2代表氢原子、羟基、(C-1-C-4)烷氧基基团、-CHC(OH)-2、COOR-f,其中R-f代表氢原子或(C-1-C-4)烷基基团、吗啉基基团、二氢吡喃基基团、(BB)基团,即(BB)、(CC)基团,即(CC)、-PO(OR-f)(OR’-f)基团,其中R-f和R’-f独立地代表氢原子或(C-1-C-4)烷基基团、氧杂环丁基、-Si(CH-3)-3基团、-NHCOO-(C-1-C-4)烷基或-CR～1R～2R～3基团。本发明进一步涉及含有它们的药物组合物,并涉及用于制备它们的合成方法。(The present invention relates to any one of the compounds of formula (Ie) or a pharmaceutically acceptable salt thereof: wherein Y is 1 Represents an aryl radical, X 2 Represents an-O-group, -NH-group, -S-group, -CO-NH-group, -NH-CO-group, -CH (OH) -group, -CH (COOH) NH group, -CH (COOCH) 3 ) NH-group, -C (OH) (CH) 2 OH) -, (AA) groups, i.e. (AA), a divalent 5-membered heteroaromatic ring containing 1,2,3 or heteroatoms, -SO 2 A group or-SO 2 -NH-group, Y 2 Represents a hydrogen atom, a hydroxyl group, or (C) 1 ‑C 4 ) Alkoxy radical, -CHC (OH) 2 、COOR f Wherein R is f Represents a hydrogen atom or (C) 1 ‑C 4 ) Alkyl radicals, morpholinyl radicals, dihydropyranyl radicals, (BB) radicals, i.e. (BB), (CC) radicals, i.e. (CC)、‑PO(OR f )(OR’ f ) Group, wherein R f And R' f Independently represents a hydrogen atom or (C) 1 ‑C 4 ) Alkyl radicals, oxetanyl radicals, -Si (CH) 3 ) 3 Group, -NHCOO- (C) 1 ‑C 4 ) Alkyl or-CR 1 R 2 R 3 A group. The invention further relates to pharmaceutical compositions containing them and to synthetic processes for preparing them.)