阅读说明：本技术 非天然氨基酸类衍生物、包含其的药物组合物及其制备方法和用途 (Non-natural amino acid derivative, pharmaceutical composition containing same, and preparation method and application thereof ) 是由 田强 宋帅 赵明亮 王太津 孙启正 蔡家强 王利春 王晶翼 于 2019-04-16 设计创作，主要内容包括：<Image he="416" wi="539" file="DDA0002652598410000011.GIF" imgContent="drawing" imgFormat="GIF" orientation="portrait" inline="no"></Image>一种式(I)的非天然氨基酸类衍生物、包含其的药物组合物、其制备方法及其作为精氨酸酶抑制剂的用途。更具体地,涉及一种非天然氨基酸类衍生物,其能够抑制精氨酸的水解,从而可用于预防或治疗与精氨酸酶活性有关的疾病或病况。(A non-natural amino acid derivative of formula (I), pharmaceutical compositions comprising the same, methods of making the same, and uses thereof as an arginase inhibitor. More particularly, it relates to a non-natural amino acid derivative which is capable of inhibiting the hydrolysis of arginine and is thus useful for the prevention or treatment of diseases or conditions associated with arginase activity.)