阅读说明：本技术 含有哌拉西林的组合物、其药物制剂及其应用 (Composition containing piperacillin, pharmaceutical preparation and application thereof ) 是由 孙天宇 于 2017-12-25 设计创作，主要内容包括：本发明提供了一种含有哌拉西林的组合物,该组合物中含有哌拉西林,还含有一定比例的氨苄西林和舒巴坦。本发明还提供了其药物制剂和应用。本发明的组合物和药物制剂可显著抑制耐药性鲍曼不动杆菌,特别是对碳青霉烯类抗生素或对头孢哌酮舒巴坦耐药的鲍曼不动杆菌感染能起到很好的治疗作用。(The invention provides a composition containing piperacillin, which contains piperacillin, ampicillin and sulbactam in a certain proportion. The invention also provides a pharmaceutical preparation and application thereof. The composition and the pharmaceutical preparation can obviously inhibit drug-resistant acinetobacter baumannii, and particularly can play a good role in treating carbapenem antibiotics or drug-resistant acinetobacter baumannii infection of cefoperazone and sulbactam.)

The composition contains also ampicillin and sulbactam, wherein the weight ratio of piperacillin to ampicillin to sulbactam is 200-400:0.02-6: 100.

The composition according to claim 1, wherein the weight ratio of piperacillin, ampicillin and sulbactam is 200-400:0.02-3:100, or 200-400:0.04-6: 100.

A composition according to claim 1, consisting of piperacillin, ampicillin and sulbactam.

A pharmaceutical formulation comprising the composition of any one of claims 1-3.

The pharmaceutical formulation of claim 4, which is an injection.

The pharmaceutical formulation of claim 5, wherein the injection is in the form of a dry powder or a solution.

The pharmaceutical preparation of claim 6, wherein the injection in the form of dry powder is a sterile powder injection or a lyophilized powder injection.

A method of treatment of a bacterial infection disease, said method comprising the use of a composition according to claims 1-3 or a pharmaceutical formulation according to claims 4-7.

The method of claim 8, wherein the bacterium is drug-resistant A.

The method of treatment according to claim 9, wherein said drug resistance is cefoperazone sulbactam resistance.