阅读说明：本技术 用于快速缓解帕金森病的左旋多巴制剂 (Levodopa formulations for rapid relief of parkinson's disease ) 是由 M·弗瑞德 R·贝蒂凯 M·M·利普 于 2013-10-21 设计创作，主要内容包括：本申请的发明名称为用于快速缓解帕金森病的左旋多巴制剂。本发明提供为帕金森病患者的运动波动提供快速缓解的方法。本发明的方法包括通过吸入来肺部施用治疗有效浓度的左旋多巴,使得与吸入所述左旋多巴前所述患者血浆中的左旋多巴浓度相比,所述患者的血浆左旋多巴浓度在吸入后10分钟或更少时间内增加了至少约200ng/ml,并且其中所述患者的血浆浓度在吸入后至少15分钟的时间段内保持增加至少约200ng/ml。本发明的方法尤其适用于治疗由患者的左旋多巴血浆水平控制较差造成的运动波动。(The invention relates to a levodopa preparation for rapidly relieving Parkinson's disease. The present invention provides methods for providing rapid relief of motor fluctuations in parkinson's disease patients. The methods of the invention comprise pulmonary administration of a therapeutically effective concentration of levodopa by inhalation such that the patient's plasma levodopa concentration increases by at least about 200ng/ml within 10 minutes or less after inhalation compared to the levodopa concentration in the patient's plasma prior to inhalation of the levodopa, and wherein the patient's plasma concentration remains increased by at least about 200ng/ml for a period of at least 15 minutes after inhalation. The methods of the invention are particularly useful for treating motor fluctuations caused by poorly controlled plasma levels of levodopa in a patient.)