免疫应答调节性物质和含有该免疫应答调节性物质的疫苗组合物
阅读说明:本技术 免疫应答调节性物质和含有该免疫应答调节性物质的疫苗组合物 (Immune response modifier and vaccine composition containing the same ) 是由 赵良济 金光成 李奈暻 朴神爱 于 2017-10-30 设计创作,主要内容包括:本发明涉及具有新颖结构的免疫应答调节性物质,和含有该免疫应答调节性物质的免疫佐剂组合物,且更具体地,涉及免疫应答调节性物质及其用途,该免疫应答调节性物质是具有降低的毒性的脂多糖(LPS)类似物。本发明的免疫应答调节性物质通过具有极好的固有免疫和诱导对特定病原体的适应性免疫应答的能力表现出免疫增强作用,且通过具有低毒性是非常安全的。此外,含有本发明的免疫应答调节性物质的疫苗含有免疫应答调节性物质和明矾,由此相较于仅使用该免疫应答调节性物质时,改善免疫增强作用。(The present invention relates to an immune response-modulating substance having a novel structure and an immunoadjuvant composition containing the same, and more particularly, to an immune response-modulating substance which is a Lipopolysaccharide (LPS) analog having reduced toxicity, and uses thereof. The immune response-modulating substance of the present invention exhibits an immunopotentiating effect by having excellent innate immunity and the ability to induce an adaptive immune response to a specific pathogen, and is very safe by having low toxicity. In addition, the vaccine containing the immune response-modulating substance of the present invention contains the immune response-modulating substance and alum, thereby improving the immunopotentiation effect as compared with the case of using only the immune response-modulating substance.)
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