阅读说明：本技术 用于治疗肾脏疾病的新化合物及其药物组合物 (Novel compounds and pharmaceutical compositions thereof for the treatment of kidney diseases ) 是由 K·E·康拉思 R·C·X·布里斯 T·J-C·M·克里斯托夫 R·范德格斯特 于 2020-04-21 设计创作，主要内容包括：本发明公开根据式I的化合物：其中R～(1)同文中定义的。本发明涉及化合物,其生产方法、包含其的药物组合物,以及利用其的治疗方法,用于预防和/或治疗施用本发明化合物可用于预防和/或治疗的多囊肾病(PKD)。(The present invention discloses compounds according to formula I: wherein R is 1 As defined herein. The present invention relates to compounds, methods for their production, pharmaceutical compositions comprising them, and methods of treatment therewith, for the prevention and/or treatment of Polycystic Kidney Disease (PKD) in which the compounds of the present invention are administered for prevention and/or treatment.)