阅读说明：本技术 双缩二胍化合物、药物组合物和在管理癌症中的用途 (Bis-biguanide compounds, pharmaceutical compositions and use in the management of cancer ) 是由 亚当·马库斯 杰西卡·科尼恩 雷切尔·科曼达 杰米·阿恩斯特 托塔·甘内什 于 2020-02-28 设计创作，主要内容包括：本公开内容涉及使用双缩二胍化合物诸如阿来西定来管理癌症的方法和包含双缩二胍化合物的药物组合物。在某些实施方案中,本公开内容涉及治疗肺癌的方法,该方法包括向有相应需要的受试者施用有效量的双缩二胍化合物。在某些实施方案中,本公开内容涉及治疗小细胞肺癌的方法,该方法包括向有相应需要的受试者施用有效量的双缩二胍化合物。在某些实施方案中,受试者被诊断患有肺癌。在某些实施方案中,受试者被诊断患有小细胞肺癌。在某些实施方案中,受试者是人类受试者。(The present disclosure relates to methods of managing cancer using bis-biguanide compounds such as alexidine and pharmaceutical compositions comprising bis-biguanide compounds. In certain embodiments, the present disclosure relates to methods of treating lung cancer comprising administering to a subject in need thereof an effective amount of a bis-biguanide compound. In certain embodiments, the present disclosure relates to methods of treating small cell lung cancer comprising administering to a subject in need thereof an effective amount of a bis-biguanide compound. In certain embodiments, the subject is diagnosed with lung cancer. In certain embodiments, the subject is diagnosed with small cell lung cancer. In certain embodiments, the subject is a human subject.)