阅读说明：本技术 用于基因组重排检测的测序方法 (Sequencing method for genome rearrangement detection ) 是由 M·科里尼 D·N·罗伯茨 于 2018-07-10 设计创作，主要内容包括：本公开涉及用于改进检测多核苷酸中存在的基因组重排比如缺失、插入、倒位和易位的单端测序方法。衔接子上的第一引发事件允许靶序列的测序,并且第二引发事件允许鉴定通过选择性扩增而扩增和加标签的序列。在相同方向上的引发事件的组合有助于读段比对和任何基因组重排的鉴定。(The present disclosure relates to single-ended sequencing methods for improved detection of genomic rearrangements, such as deletions, insertions, inversions, and translocations, present in a polynucleotide. A first priming event on the adapter allows sequencing of the target sequence and a second priming event allows identification of sequences amplified and tagged by selective amplification. The combination of priming events in the same direction facilitates read alignment and identification of any genomic rearrangements.)