用于预防或治疗骨相关疾病的药物组合物

文档序号:1449221 发布日期:2020-02-18 浏览:14次 >En<

阅读说明:本技术 用于预防或治疗骨相关疾病的药物组合物 (Pharmaceutical composition for preventing or treating bone-related diseases ) 是由 徐廷泽 文硕晙 金圣镇 于 2018-05-30 设计创作,主要内容包括:本发明涉及一种用于预防或治疗骨相关疾病的药物组合物;其促进前成骨细胞分化为成骨细胞以诱导产生矿化结节,并且在同时抑制骨髓细胞分化为破骨细胞和抑制破骨细胞的功能,从而有效控制骨内稳态并在预防或治疗骨相关疾病中十分有用。此外,本发明还涉及一种用于预防或治疗更年期疾病(尤其是更年期骨疾病)的药物组合物;其中所述药物组合物提升海绵状骨体积和促进前成骨细胞的分化为成骨细胞以诱导产生矿化结节,并同时抑制骨髓细胞分化为破骨细胞抑制和破骨细胞的功能,从而有效控制骨内稳态并在预防或治疗骨相关疾病中十分有用。(The present invention relates to a pharmaceutical composition for preventing or treating bone-related diseases; it promotes differentiation of preosteoblasts into osteoblasts to induce the production of mineralized nodules, and is very useful in simultaneously inhibiting differentiation of bone marrow cells into osteoclasts and inhibiting the function of osteoclasts, thereby effectively controlling bone homeostasis and in preventing or treating bone-related diseases. In addition, the present invention relates to a pharmaceutical composition for preventing or treating a climacteric disorder (particularly a climacteric bone disorder); wherein the pharmaceutical composition promotes the spongy bone volume and promotes the differentiation of preosteoblasts into osteoblasts to induce the production of mineralized nodules, and simultaneously inhibits the differentiation of bone marrow cells into osteoclast inhibition and osteoclast function, thereby effectively controlling bone homeostasis and being very useful in the prevention or treatment of bone-related diseases.)

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