阅读说明：本技术 治疗痤疮、脂溢性皮炎的药物及其制备方法 (Medicine for treating acne and seborrheic dermatitis and preparation method thereof ) 是由 王宏磊 于 2019-09-11 设计创作，主要内容包括：本发明公开了一种治疗痤疮、脂溢性皮炎的药物,治疗痤疮、脂溢性皮炎的药物包括以下组分：椰油酰羟乙磺酸钠0.1～10份；月桂酰肌氨酸钠1～30份；椰油酰胺丙基羟基磺基甜菜碱0.1～10份；烷基酰胺甜菜碱0.1～10份；维生素原B5 0.1～5份；迷迭香叶油0.1～5份；苯甲醇0.1～1份；脱氢醋酸1～10份；水50～99份。本发明制备的治疗痤疮、脂溢性皮炎的药物,具有药物副作用小、效果显著。(The invention discloses medicines for treating acne and seborrheic dermatitis, which comprise 0.1-10 parts of sodium cocoyl isethionate, 1-30 parts of sodium lauroyl sarcosinate, 0.1-10 parts of cocamidopropyl hydroxysultaine, 0.1-10 parts of alkylamide betaine, 50.1-5 parts of provitamin B, 0.1-5 parts of rosemary leaf oil, 0.1-1 part of benzyl alcohol, 1-10 parts of dehydroacetic acid and 50-99 parts of water.)

1, A medicine for treating acne and seborrheic dermatitis, which is characterized in that the medicine for treating acne and seborrheic dermatitis comprises the following components:

2. the medicament for treating acne and seborrheic dermatitis according to claim 1, further comprising 0.1-10 parts of aloe vera leaf juice.

3. The medicament for treating acne and seborrheic dermatitis according to claim 1, further comprising 0.1-5 parts of polyquaternium-7.

4. The medicament for treating acne and seborrheic dermatitis according to claim 1, further comprising 0.1-1 part of tetrasodium ethylenediamine tetraacetate.

5. The medicament for treating acne and seborrheic dermatitis according to claim 1, further comprising 0.01-0.05 part of ascorbic acid.

6. The medicament for treating acne and seborrheic dermatitis according to claim 1, further comprising 0.1-1 part of citric acid.

7. The method for preparing a medicament for treating acne and seborrheic dermatitis according to any one of claims 1 to 6 to , wherein the preparation method comprises the steps of adding aloe vera leaf juice into water, stirring for 0.1 to 1 hour, then adding sodium cocoyl isethionate, sodium lauroyl sarcosinate, cocoamidopropyl hydroxysultaine, alkylamidobetaine, provitamin B5, rosemary leaf oil, polyquaternium-7, benzyl alcohol, dehydroacetic acid, tetrasodium ethylenediamine tetraacetate, ascorbic acid and citric acid, and stirring for 3 to 5 hours to obtain the medicament for treating acne and seborrheic dermatitis.

Technical Field

The invention relates to the field of medicaments for treating acne, in particular to medicaments for treating acne and seborrheic dermatitis and a preparation method thereof.

Background

The excessive secretion of sebum, which is produced in developed sebaceous glands, is considered to be important reasons for inducing seborrheic dermatitis and acne, the sebaceous glands are opened in the mouth of the hair follicle, denier hair follicle mouth is blocked, the stimulation of excessive fatty acid produced by excessive sebum metabolism and the action of propionibacterium acnes excessively proliferating in a closed environment cause inflammatory reaction of the skin.

Disclosure of Invention

Aiming at the defects, the invention aims to provide medicines for treating acne and seborrheic dermatitis and a preparation method thereof, which have efficient cleaning effect, excellent compatibility and no toxicity or harm to the atmospheric environment and human bodies.

The technical scheme of the invention is summarized as follows:

A medicine for treating acne and seborrheic dermatitis, wherein the medicine for treating acne and seborrheic dermatitis comprises the following components:

preferably, the medicine for treating acne and seborrheic dermatitis further comprises 0.1-10 parts of aloe vera leaf juice.

Preferably, the medicine for treating acne and seborrheic dermatitis further comprises 0.1-5 parts of polyquaternium-7.

Preferably, the medicine for treating acne and seborrheic dermatitis further comprises 0.1-1 part of tetrasodium ethylenediamine tetraacetate.

Preferably, the medicine for treating acne and seborrheic dermatitis further comprises 0.01-0.05 part of ascorbic acid.

Preferably, the medicine for treating acne and seborrheic dermatitis further comprises 0.1-1 part of citric acid.

A preparation method of a medicine for treating acne and seborrheic dermatitis, wherein the preparation method comprises the following steps of adding aloe vera leaf juice into water, stirring for 0.1-1 h, then adding sodium cocoyl isethionate, sodium lauroyl sarcosinate, cocamidopropyl hydroxysultaine, alkylamide betaine, provitamin B5, rosemary leaf oil, polyquaternium-7, benzyl alcohol, dehydroacetic acid, tetrasodium ethylenediamine tetraacetate, ascorbic acid and citric acid, and stirring for 3-5 h to obtain the medicine for treating acne and seborrheic dermatitis.

The invention has the beneficial effects that:

(1) the medicine for treating acne and seborrheic dermatitis prepared by the invention has small side effect and obvious effect.

(2) The medicine for treating acne and seborrheic dermatitis prepared by the invention is characterized in that cocoyl isethionate is added to regulate and control epithelial cell differentiation and growth, sodium lauroyl sarcosinate is colorless to yellowish transparent liquid, is good in foaming performance, rich and stable in foam, high in tolerance to hard water and electrolyte, and can be used with sodium cocoyl isethionate under the synergistic effect to improve the antibacterial performance, promote proliferation of basal cells and inhibit hyperkeratosis of epithelial of sebaceous gland ducts, cocoamidopropyl hydroxysultaine is zwitterionic surfactants, is used with sodium cocoyl isethionate and sodium lauroyl sarcosinate, has good compatibility, is nontoxic, small in irritation, is easy to dissolve in water, has excellent thickening property, softness, extremely strong bactericidal property and water resistance, inhibits growth of propionibacterium acnes, has good cleaning and disinfecting performance, provitamin B5 is beneficial to wound healing and regulation of skin immunity and inflammation, and dehydroacetic acid is low-toxicity, high-efficiency antiseptic, antimildew regulator, bacteria and bacteria inhibition of skin inflammation, and proliferation inhibition of bacteria.

Detailed Description

The present invention is further described in conjunction with the following examples to enable those skilled in the art to practice the invention in light of the above teachings.

The proposal provides medicaments for treating acne and seborrheic dermatitis, and the medicaments for treating the acne and the seborrheic dermatitis comprise the following components:

the sodium cocoyl isethionate is novel anionic surfactant which is prepared by esterifying hydroxyethyl sodium sulfonate and coconut fatty acid, is high in stability, not easy to oxidize and good in biodegradation performance, hydrophilic parts comprise ethoxy groups and sulfonic acid groups to form large diffusion polar groups, plays a leading role in the sodium cocoyl isethionate, epithelial cell differentiation and growth are regulated and controlled by adding the sodium cocoyl isethionate, sodium lauroyl sarcosinate is colorless to yellowish transparent liquid, is good in foaming performance, rich and stable in foam, high in tolerance to hard water and electrolyte, and has a synergistic effect with the sodium cocoyl isethionate to improve antibacterial performance, promote proliferation of basal cells and inhibit hyperkeratosis of epithelial tubes of sebaceous glands, cocamidopropyl hydroxysultaine is an oil amphoteric ion surfactant, combines with the sodium cocoyl isethionate and the sodium lauroyl sarcosinate, is good in compatibility, small in irritation, has strong water astringency, has strong astringent effect, has strong bactericidal effect, has good stability, is stable in skin, is used for inhibiting inflammation of acne, has a low in the growth of camphor, the skin, the inflammation of mucormophthalmia, the skin, the inflammation of the skin, the skin regeneration of mucormophthalmia, the skin, the inflammation of the low toxicity of camphor, the mucormophthalmia, the inflammation of the mucoid, the skin, the inflammation of the mucoid.

As another embodiment, the lotion further comprises 0.1-10 parts of Aloe Barbadensis Miller leaf juice, which is bitter and cold in taste, and has effects of clearing heat, promoting healing, and protecting skin wound and burn.

In another embodiment, the skin care composition further comprises 0.1-5 parts of polyquaternium-7. polyquaternium-7 has excellent wettability, flexibility and film-forming property, and can improve the skin wettability by adding polyquaternium-7, dissolve acne and reduce the cohesion of stratum corneum.

As another embodiment, the composition further comprises 0.1-1 part of tetrasodium ethylenediamine tetraacetate, and the stability of the medicament is improved by adding the tetrasodium ethylenediamine tetraacetate.

In another embodiment , the skin care product further comprises ascorbic acid in an amount of 0.01 to 0.05 parts by weight, wherein the ascorbic acid is formed by an antibody and collagen, and is used for repairing tissues and promoting skin repair.

As another embodiment, the composition further comprises 0.1-1 part of citric acid, wherein the citric acid has the effects of inhibiting bacteria, inhibiting the growth of propionibacterium acnes and regulating the immunity and inflammation of pathological skin, can dissolve comedos, can reduce the cohesive force of stratum corneum, can loosen comedos and is beneficial to removing comedos.

A medicine for treating acne and seborrheic dermatitis is prepared by adding Aloe Barbadensis Miller leaf juice into water, stirring for 0.1-1 h, adding sodium cocoyl isethionate, sodium lauroyl sarcosinate, cocamidopropyl hydroxysultaine, alkylamide betaine, provitamin B5, rosemary leaf oil, polyquaternium-7, benzyl alcohol, dehydroacetic acid, tetrasodium ethylenediamine tetraacetate, ascorbic acid, and citric acid, and stirring for 3-5 h to obtain the medicine for treating acne and seborrheic dermatitis.

Specific examples and comparative examples are listed below: