阅读说明：本技术 表达多个巨细胞病毒(cmv)抗原的mva载体及其用途 (MVA vectors expressing multiple Cytomegalovirus (CMV) antigens and uses thereof ) 是由 费利克斯·乌索 唐·J·戴蒙德 于 2018-07-13 设计创作，主要内容包括：所公开的是一种共表达多个人巨细胞病毒(HCMV)抗原以激发针对HCMV感染的有效的体液和细胞免疫应答的表达系统。该表达系统可包括被插入多个核酸序列的载体,该多个核酸序列编码通过一个或多个连接序列连接的HCMV抗原的多个亚单位,使得该亚单位同时被共表达。所公开的还有包含该表达系统或载体的疫苗组合物以及使用该疫苗组合物预防或治疗HCMV感染的方法。(Disclosed is an expression system that co-expresses multiple Human Cytomegalovirus (HCMV) antigens to elicit an effective humoral and cellular immune response against HCMV infection. The expression system may comprise a vector into which a plurality of nucleic acid sequences encoding a plurality of subunits of HCMV antigen linked by one or more linking sequences are inserted such that the subunits are co-expressed simultaneously. Also disclosed are vaccine compositions comprising the expression systems or vectors and methods of using the vaccine compositions to prevent or treat HCMV infection.)