阅读说明：本技术 用于治疗IgE驱动的B细胞疾病的氯氮平 (Clozapine for the treatment of IgE driven B cell disorders ) 是由 S·乔利斯 H·阿什拉菲安 D·麦克黑尔 于 2019-01-31 设计创作，主要内容包括：本发明涉及化合物氯氮平及其主要代谢物去甲氯氮平和其前药以及药学上可接受的盐和溶剂化物,用于治疗或预防致病性的IgE驱动的B细胞疾病。本发明还提供了包含所述化合物的药物组合物。(The present invention relates to the compound clozapine and its major metabolite norclozapine and its prodrugs as well as pharmaceutically acceptable salts and solvates thereof for use in the treatment or prevention of pathogenic IgE driven B cell diseases. The invention also provides pharmaceutical compositions comprising said compounds.)