阅读说明：本技术 一种铁皮石斛叶微生态制剂的制备方法 (Preparation method of dendrobium officinale leaf microecological preparation ) 是由 邵平 方静宇 林杨 陈碧莲 冯思敏 于 2021-05-26 设计创作，主要内容包括：本发明公开了一种铁皮石斛叶微生态制剂的制备方法,所述制作方法包括如下步骤：(1)由铁皮石斛叶提取得到纯化的分子量在50-100kDa之间的铁皮石斛叶多糖；(2)取步骤(1)得到的铁皮石斛叶多糖与肠粘附材料于水中混匀,喷雾干燥后即得调节糖尿病结肠菌群的铁皮石斛叶微生态制剂；所述的肠粘附材料为抗消化淀粉和卡波姆的组合,所述铁皮石斛叶多糖与抗消化淀粉、卡波姆的投料质量比为0.2-0.3：0.02-0.03：0.05-0.06。本发明在制备过程中,筛选出了高降血糖活性的石斛叶多糖,将其和结肠粘附材料混合制成制剂,使制剂在结肠处释放给药,增加了多糖在结肠中的作用时间,从而达到治疗肠道菌群失调引起的肠道功能紊乱疾病的目的。(The invention discloses a preparation method of a dendrobium officinale leaf microecological preparation, which comprises the following steps: (1) extracting purified Dendrobium officinale leaf polysaccharide with molecular weight of 50-100kDa from Dendrobium officinale leaf; (2) uniformly mixing the dendrobium officinale leaf polysaccharide obtained in the step (1) and an intestinal adhesion material in water, and performing spray drying to obtain the dendrobium officinale leaf microecological preparation for regulating the colonic flora for diabetes; the intestinal adhesion material is a combination of anti-digestion starch and carbomer, and the feeding mass ratio of the dendrobium officinale leaf polysaccharide to the anti-digestion starch to the carbomer is 0.2-0.3: 0.02-0.03: 0.05-0.06. In the preparation process, the dendrobium leaf polysaccharide with high hypoglycemic activity is screened out and mixed with the colon adhesion material to prepare the preparation, so that the preparation is released and administered at the colon, the action time of the polysaccharide in the colon is prolonged, and the aim of treating intestinal dysfunction diseases caused by intestinal dysbacteriosis is fulfilled.)