阅读说明：本技术 苯偶酰腙-1-萘甲醛西弗碱的用途 (Application of benzil hydrazone-1-naphthaldehyde Schiff base ) 是由 邢殿香 刘帅 谭学杰 于 2019-11-12 设计创作，主要内容包括：本发明涉及药物化学和功能材料领域,具体为苯偶酰二腙或苯偶酰单腙与1-萘甲醛反应生成的西弗碱在抗癌、抗菌药物中的用途,也包括其在医药材料、功能材料等领域的用途；苯偶酰二腙-N,N’-二(1-甲酰基萘)外观呈浅黄色梭状晶体,熔点201.0-203.0℃,分子式C<Sub>36</Sub>H<Sub>26</Sub>N<Sub>4</Sub>；苯偶酰单腙-N-1-甲酰基萘外观呈黄色块状晶体,熔点135.2-136.7℃,分子式C<Sub>25</Sub>H<Sub>18</Sub>N<Sub>2</Sub>O；二者结构如下：<Image he="181" wi="700" file="DDA0002269464020000011.GIF" imgContent="drawing" imgFormat="GIF" orientation="portrait" inline="no"></Image>以上两种物质对肺癌细胞、乳腺癌细胞及大肠杆菌、金黄色葡萄球菌都有一定的抑制活性,可用于抗肿瘤、抗菌药物和医药材料。(The invention relates to the field of medicinal chemistry and functional materials, in particular to application of Schiff base generated by reaction of benzildihydrazone or benzildihydrazone and 1-naphthaldehyde in anticancer and antibacterial drugs, and also application of the Schiff base in the fields of medical materials, functional materials and the like; the benzil dihydrazone-N, N' -di (1-formylnaphthalene) is light yellow fusiform crystal in appearance, the melting point is 201.0-203.0 ℃, and the molecular formula is C 36 H 26 N 4 (ii) a The benzil monohydrazone-N-1-formyl naphthalene is yellow blocky crystal in appearance, has a melting point of 135.2-136.7 ℃, and has a molecular formula C 25 H 18 N 2 O; the two structures are as follows： The above two substances have certain inhibitory activity on lung cancer cell, breast cancer cell, Escherichia coli, and Staphylococcus aureus, and can be used in antitumor and antibacterial drugs and medicinal materials.)

1. The application of two compound crystals or other pharmaceutically acceptable salts shown as the following formula in preparing a medicament for preventing and/or treating tumors is characterized in that: the tumors are lung cancer and breast cancer; the benzil dihydrazone-N, N' -di (1-formylnaphthalene) is light yellow fusiform crystal in appearance, the melting point is 201.0-203.0 ℃, and the molecular formula is C ₃₆H ₂₆N ₄(ii) a The benzil monohydrazone-N-1-formyl naphthalene is yellow blocky crystal in appearance, has a melting point of 135.2-136.7 ℃, and has a molecular formula C ₂₅H ₁₈N ₂O; the structures of the two are as follows:

2. the use of two compounds as claimed in claim 1 in antibacterial medicaments or antibacterial materials, which are effective in inhibiting the proliferation of escherichia coli and staphylococcus aureus.