阅读说明：本技术 用于预防流感病毒传播的化合物和方法 (Compounds and methods for preventing influenza virus transmission ) 是由 熨斗武志 野田阳弘 吉田立 宍户贵雄 马场薰 A·C·赫特 L·Y·Y·李 S·维尔杜 于 2020-03-26 设计创作，主要内容包括：本发明涉及用于预防流感传播的方法,其中所述方法包括对具有流感病毒感染的患者、本文称作“源头患者”施用有效量的化合物或其药学上可接受的盐,其中所述化合物具有式(I)和(II)之一。用于本发明的化合物降低源头患者的流感病毒的传染性,且由此与对照患者相比降低源头患者触发流感流行或流感大流行的风险。因此,本发明的一个方面涉及用于预防流感流行或流感大流行的方法,其中所述方法包括对具有流感病毒感染的患者(源头患者)施用有效量的化合物,其中将所述化合物施用于城市或国家人口的全部流感感染者的至少10％,且其中所述化合物具有式(I)和(II)之一或为其药学上可接受的盐。(The present invention relates to a method for preventing the spread of influenza, wherein said method comprises administering to a patient having an influenza virus infection, herein referred to as the "source patient", an effective amount of a compound, or a pharmaceutically acceptable salt thereof, wherein said compound has one of the formulae (I) and (II). The compounds for use in the present invention reduce the infectivity of influenza virus in a source patient, and thereby reduce the risk of triggering an influenza pandemic or flu pandemic in the source patient compared to a control patient. Accordingly, one aspect of the present invention relates to a method for preventing influenza pandemics or flu pandemics, wherein said method comprises administering an effective amount of a compound to a patient having an influenza virus infection (source patient), wherein said compound is administered to at least 10% of all influenza infected persons of a city or national population, and wherein said compound has one of the formulae (I) and (II) or is a pharmaceutically acceptable salt thereof.)