用于预防和/或治疗动物中的疼痛的4-[5-[(rac)-1-[5-(3-氯苯基)-3-异噁唑基]乙氧基]-4-甲基-4H-1,2,4-三唑-3-基]吡啶

文档序号:411076 发布日期:2021-12-17 浏览:17次 >En<

阅读说明:本技术 用于预防和/或治疗动物中的疼痛的4-[5-[(rac)-1-[5-(3-氯苯基)-3-异噁唑基]乙氧基]-4-甲基-4H-1,2,4-三唑-3-基]吡啶 (4- [5- [ (rac) -1- [5- (3-chlorophenyl) -3-isoxazolyl ] ethoxy ] -4-methyl-4H-1, 2, 4-triazol-3-yl ] pyridine for the prevention and/or treatment of pain in an animal ) 是由 克拉斯·图林 于 2019-11-22 设计创作,主要内容包括:本发明涉及4-[5-[(rac)-1-[5-(3-氯苯基)-3-异噁唑基]乙氧基]-4-甲基-4H-1,2,4-三唑-3-基]吡啶(TT00),或其药学上可接受的盐、非对映异构体、对映异构体、同位素、前药或代谢物或其混合物,或包含所述TT00的药物组合物,用于预防和/或治疗动物诸如狗、猫或马中的疼痛,诸如慢性疼痛和/或周围疼痛和/或与关节炎诸如骨关节炎有关的疼痛,或用于预防和/或治疗动物诸如狗、猫或马中的所述疼痛与b)GERD或c)焦虑的组合。(The present invention relates to 4- [5- [ (rac) -1- [5- (3-chlorophenyl) -3-isoxazolyl ] ethoxy ] -4-methyl-4H-1, 2, 4-triazol-3-yl ] pyridine (TT00), or a pharmaceutically acceptable salt, diastereomer, enantiomer, isotope, prodrug or metabolite thereof or a mixture thereof, or a pharmaceutical composition comprising said TT00, for use in the prevention and/or treatment of pain, such as chronic pain and/or peripheral pain and/or pain associated with arthritis, such as osteoarthritis, in an animal, such as a dog, cat or horse, or for use in the prevention and/or treatment of said pain in an animal, such as a dog, cat or horse, in combination with b) GERD or c) anxiety.)

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