阅读说明：本技术 Trbc使用的分子评估 (Molecular assessment of TRBC usage ) 是由 S.奥诺哈 M.查皮加 B.马 于 2019-07-18 设计创作，主要内容包括：本发明涉及确定细胞的T细胞受体β链(TRBC)基因类型的方法,该方法包括(a)确定所述细胞中表达的J基因类型,和(b)从(a)推断所述细胞中表达的TRBC基因类型。本发明进一步涉及靶向T细胞受体β链(TRBC)1型的CAR T细胞或靶向T细胞受体β链(TRBC)2型的CAR T细胞的用途。本发明进一步涉及医学治疗的方法和核酸探针。(The present invention relates to a method of determining the T cell receptor beta chain (TRBC) gene type of a cell, the method comprising (a) determining the J gene type expressed in the cell, and (b) inferring the TRBC gene type expressed in the cell from (a). The invention further relates to the use of a CAR T cell targeting T cell receptor beta chain (TRBC) type 1 or a CAR T cell targeting T cell receptor beta chain (TRBC) type 2. The invention further relates to methods of medical treatment and nucleic acid probes.)