阅读说明：本技术 用嵌合体诱饵治疗脊柱病症 (Treatment of spinal disorders with chimeric baits ) 是由 舛田浩一 中泽隆弘 于 2019-12-24 设计创作，主要内容包括：本文提供用于治疗脊柱病症的方法和组合物。具体而言,能够结合于两种转录因子(NF-κB和STAT6)的DNA结合位点的双链寡核苷酸诱饵用于治疗椎间盘退化、再生软骨细胞细胞外基质、脊柱疼痛和促进椎间盘细胞中的蛋白聚糖合成的用途。(Provided herein are methods and compositions for treating spinal disorders. In particular, the use of a double-stranded oligonucleotide decoy capable of binding to the DNA binding sites of two transcription factors (NF- κ B and STAT6) for the treatment of disc degeneration, regeneration of chondrocyte extracellular matrix, spinal pain and promotion of proteoglycan synthesis in intervertebral disc cells.)